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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRF
All Species:
26.36
Human Site:
S446
Identified Species:
41.43
UniProt:
P11831
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11831
NP_003122.1
508
51593
S446
S
T
M
Q
V
S
H
S
Q
V
Q
E
P
G
G
Chimpanzee
Pan troglodytes
XP_518487
508
51590
S446
S
T
M
Q
V
S
H
S
Q
V
Q
E
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001093365
508
51688
S446
S
T
M
Q
V
S
H
S
Q
V
Q
E
P
G
G
Dog
Lupus familis
XP_852302
508
51510
S446
S
T
M
Q
V
S
H
S
Q
V
Q
E
Q
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM73
504
51229
S442
S
T
M
Q
V
S
H
S
Q
V
Q
E
P
G
G
Rat
Rattus norvegicus
NP_001102772
504
51157
S442
S
T
M
Q
V
S
H
S
Q
V
Q
E
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517936
150
15822
Q90
Q
V
S
H
G
Q
V
Q
E
Q
G
G
V
P
Q
Chicken
Gallus gallus
Q90718
375
39146
V315
M
Q
V
S
H
S
Q
V
Q
D
Q
G
G
V
P
Frog
Xenopus laevis
P23790
448
46097
H388
A
P
Q
M
Q
V
S
H
T
Q
E
Q
G
G
V
Zebra Danio
Brachydanio rerio
NP_001103996
539
55032
T479
S
A
M
H
V
S
H
T
P
N
Q
D
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24535
449
47603
H388
R
Q
L
I
Q
S
G
H
L
Q
V
H
A
E
E
Honey Bee
Apis mellifera
XP_001120126
351
36852
S290
G
S
Q
H
A
P
P
S
H
A
Q
H
A
H
L
Nematode Worm
Caenorhab. elegans
NP_492296
327
35027
N267
K
I
T
P
P
S
S
N
M
N
N
A
A
F
L
Sea Urchin
Strong. purpuratus
XP_796790
410
43027
Q350
V
T
M
L
T
A
P
Q
S
S
M
S
P
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11746
286
32783
Q226
H
P
Q
Q
S
Q
P
Q
Q
Q
Q
Q
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
97.2
N.A.
96.4
96.6
N.A.
22.8
66.5
72.4
57.7
N.A.
35
33.4
28.7
33.8
Protein Similarity:
100
99.8
98.8
98
N.A.
97.4
97.6
N.A.
24
69.6
76.9
67.7
N.A.
48.8
40.3
41.1
45.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
20
6.6
53.3
N.A.
6.6
13.3
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
26.6
26.6
66.6
N.A.
13.3
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
7
0
0
0
7
0
7
20
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
7
40
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
7
0
0
0
7
0
7
0
0
0
7
14
14
54
54
% G
% His:
7
0
0
20
7
0
47
14
7
0
0
14
0
7
0
% H
% Ile:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
7
0
0
0
0
7
0
0
0
0
0
14
% L
% Met:
7
0
54
7
0
0
0
0
7
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
14
7
0
0
0
0
% N
% Pro:
0
14
0
7
7
7
20
0
7
0
0
0
40
7
7
% P
% Gln:
7
14
20
47
14
14
7
20
54
27
67
14
14
7
14
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
47
7
7
7
7
67
14
47
7
7
0
7
7
0
0
% S
% Thr:
0
47
7
0
7
0
0
7
7
0
0
0
0
0
0
% T
% Val:
7
7
7
0
47
7
7
7
0
40
7
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _